Our previous studies [10] found that some of the gastric cancer-related mRNAs were co-expressed with UCA1 and were involved in the PI3K-Akt-mTOR signaling pathway, so we investigated whether the induction of proliferation, apoptosis, and invasion in gastric cancer cells by UCA1 involved regulation of the key PI3K-Akt-mTOR signaling proteins and their downstream mediators. The gene discussed is AKT1; the disease is gastric cancer.