CAV1 and breast neoplasm: In addition, the use of subcutaneous LLCs, orthotopic E0771, and transgenic PyMT breast tumors, which all developed larger spontaneous lung metastasis in Cav1 KO→WT mice, allows us to further speculate on the results obtained upon intravenous injection of LLC cells, which also showed enhanced metastatic growth in Cav1 KO→WT mice.