The minor A allele that encodes the variant leucine residue of NLRP7 p.S361L had a higher frequency in all IBD subgroups compared with controls [Freq[CD] = 0.100%, Freq[UC] = 0.200%, Freq[cont] = 0.035%] and was significantly associated with UC (P = 3.9 × 10-3, odds ratio [OR] = 4.79, 95% confidence onterval [CI]: 1.60 - 14.00), also after correction for multiple testing [Table 1]. Here, NLRP7 is linked to inflammatory bowel disease.