Also grading (2 and 3 vs. grade 1 HR: 2.65; 95%CI: 1.53–4.59; p 0.001) and molecular subtype (Her2+ and Triple negative vs Luminal tumors HR: 3.79; 95%CI: 2.16–6.66; p <0.001) seems to influence DFS, but at the multivariable analysis only molecular subtype seems to independently influence the DFS with a HR of 2.63 (95%CI: 1.33–5.18; p 0.005) or a HR of 2.65 (95%CI: 1.34–5.22; p 0.005), respectively for the model with tumor size or TV, corrected for the other prognostic factors. Here, ERBB2 is linked to neoplasm.