CEACAM8 and neoplasm: Rao et al found high intratumoral neutrophil counts, defined as >60 CD66b+ cells per tumor microarray (TMA) spot, to be associated with worse survival.[11] However, as previously mentioned, the CD66b marker is not specific for neutrophils and the use of TMA fails to account for tumor heterogeneity in the same way that our method of scoring 20 separate HPFs on whole sections does.