In feces, Christensenella associated with T1D and correlated negatively with fecal acetate (Spearman r = -0.416, p<0.05), whereas Subdoligranulum correlated significantly with plasma markers of endotoxemia (LBP, r = 0.519, p<0.001) and inflammation (CRP, r = 0.362, p<0.05, S2A Fig) in T1D. The gene discussed is CRP; the disease is serum lipopolysaccharide activity.