As obviously shown in Figure 7(a), the mRNA expression of CXCL3, ELF5, and TIMP1 significantly increased in CRC tissues compared with matched adjacent normal tissues, whereas PHLPP2 mRNA expression was decreased in CRC tissues; and these results were further confirmed by TCGA database (Figure 7(b)). This evidence concerns the gene PHLPP2 and colorectal carcinoma.