More significantly, besides the aberrant expression of TIMP1 being confirmed by previous study, it is a marker of clinical significance in the diagnosis and prognosis of patients with colon carcinomas [46]; to the best of our knowledge, the current study is the first to report the prognostic value of CXCL3, ELF5, and PHLPP2 in CRC. This evidence concerns the gene CXCL3 and colon carcinoma.