Interestingly, DC cultured with tumor-derived supernatant also exhibited increased expression of the scavenger receptor MSR1, suggesting that the accumulation of lipids in these DCs might arise from tumor-derived factors that promote DC uptake of fatty acids in the form of lipoproteins, as triglycerides are typically not taken up by DC but can be synthesized from lipoprotein precursors within cells. Here, MSR1 is linked to neoplasm.