Though the mechanistic basis for these findings was not further studied in the B16 melanoma model, the authors reported analogous findings in the MC38 colon adenocarcinoma model, where antibiotic treatment decreased both the frequency of TNF-producing tumor-infiltrating DC (and other leukocytes) as well as CD86 expression and IL-12p40 production by tumor-associated DC. The gene discussed is CD86; the disease is neoplasm.