As mentioned previously in the Section “Introduction,” it has been revealed that AD risk is linked with ZCWPW1, SORL1, SLC24A4, RIN3, PTK2B, PLD3, PICALM, NME8, MS4A6E, MS4A4E, MS4A4A, MEF2C, INPP5D, HLA-DRB4, HLA-DRB1, FERMT2, EPHA1, DSG2, CR1, CLU, CELF1, CD33, CD2AP, CASS4, BIN1, APOE, and ABCA7 in GWAS and meta-analyses (7–12). Here, CASS4 is linked to Alzheimer disease.