Drugs that block cardiac ion channels encoded by the human-ether-à-go-go Related Gene (hERG) and consequently prolong the QT interval are associated with increased risk of Torsade de Pointes (TdP), a potentially lethal arrhythmia that caused several drugs to be withdrawn from market (Gintant et al., 2016). Here, KCNH2 is linked to torsades de pointes.