ACHE and Cognitive impairment: Besides the facts that memory impairment induced by scopolamine is a result of an increase in AChE activity and brain oxidative status (Chen et al., 2008; Konar et al., 2011), it can be also assumed that scopolamine impairs neurogenesis in the brain which in turn leads to cognitive deficits as in AD (Demars et al., 2010; Lazarov and Marr, 2013).