To further substantiate the prognostic power of the investigated parameters, we next performed univariate Cox-regression analyses of routinely measured tumor markers for hepatobiliary malignancies (CA19-9, CEA and AFP) and standard laboratory markers (haemoglobin, leucocyte count, thrombocyte count, sodium, potassium, calcium, AST, ALT, bilirubin, GGT, AP, and CRP) as well as routine clinical and pathological parameters (age, gender, body mass index (BMI) and TNM-stages). This evidence concerns the gene AFP and neoplasm.