Furthermore, a deletion of 1 base within VWF exon 4 was detected in affected Scottish Terriers (Venta et al. 2000) and another 1-base deletion within exon 7 is the putative cause for VWD in the Shetland Sheepdog (Venta et al. 1998). The gene discussed is VWF; the disease is von Willebrand disease (hereditary or acquired).