ROC curves proved the superiority of MMP-9 for discriminating NSCLC cases with an AUC of 0.852, followed by MMP-9/TIMP1 (AUC 0.781), MMP-1 (AUC 0.729) and MMP-7 with a modest discriminatory capacity (AUC 0.658). Here, TIMP1 is linked to non-small cell lung carcinoma.