REN and anti-neutrophil cytoplasmic antibody-associated vasculitis: Though proteinuria is a major factor in the progression of kidney damage, and inhibition of the renin-angiotensin-aldosterone system may improve the renal outcome [23–25], we did not found that the use of ACEI/ARB or proteinuria was independently associated with the long-term renal outcomes of AAV patients in the study.