In one such study of NSCLC, treatment with the anti-PD-1 antibody nivolumab was shown to be more effective than docetaxel chemotherapy in patients with PD-L1 positive, but not PD-L1 negative, tumors at all classified levels of PD-L1 expression (≥1%, ≥5%, and ≥10% of tumor cells) [11]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.