This assertion is supported by the results of a study of the anti-PD-L1 antibody atezolizumab (MPDL3280A) in multiple solid tumors, in which positive treatment responses were significantly associated with higher baseline levels of TIL-expressed PD-L1; in this study, there was no correlation between treatment response and PD-L1 expression on tumor cells. Here, CD274 is linked to neoplasm.