Co-recruitment of JMJD2C and Prmt1 (protein arginine methyltransferase 1) by MOZ (monocytic leukemia zinc finger protein)-TIF2 (transcriptional intermediary factor 2) and MLL (malignant lymphoma with leukemia)-GAS7 (Growth arrest-specific 7) in acute promyelocytic leukemia (APL) has implied the possible mechanism of JMJD2C in oncogenesis. This evidence concerns the gene PRMT1 and acute promyelocytic leukemia.