A number of studies have explored the associations between CAV-1 genetic polymorphisms and the risk of various cancer types including hepatocellular carcinoma [13], gastric cancer [14], esophageal cancer [18], colorectal cancer [19], renal cell carcinoma [20], prostate cancer [15], bladder cancer [21] and leukemia [22]. The gene discussed is CAV1; the disease is leukemia.