AFP and neoplasm: The selection items for HCC LT primarily include data on tumor histology, including tumor number, diameter, volume, histological level and microvascular invasion [5-8] (e.g., the Milan criteria, the UCSF criteria and the Hangzhou criteria), serum biomarkers such as alpha-fetoprotein (AFP) and micro-RNAs [7, 9] (e.g., the Hangzhou criteria) and the response to transarterial chemoembolization(TACE)[10].