MMPP (0-15 μg/mL) enhanced the expression of apoptotic proteins such as Bax, cleaved caspase-3 and cleaved caspase-8 while decreased the expression of anti-apoptotic protein Bcl-2 in HCT116 (Figure 2A) and SW480 (Figure 2B) colon cancer cells. The gene discussed is CASP8; the disease is malignant colon neoplasm.