The mean aminotransferase (ALT) and AST levels at the end of treatment and at 24 w post-treatment were significantly decreased compared with the baseline levels (ALT: 57.8 ± 38.1 vs 19.8 ± 14.2, P01 < 0.001; 57.8 ± 38.1 vs 17.3 ± 6.8, P02<0.001; AST: 53.2 ± 31.8 vs 24.4 ± 9.9, P01 < 0.001; 53.2 ± 31.8 vs 22.7 ± 6.9, P02 < 0.001) (Table 2), whereas one decompensated cirrhotic patient (LSM = 41.2 kPa, mild ascites) treated with SOF/LDV developed a liver injury at the end of treatment (ALT = 101 IU/L; AST = 72 IU/L). Here, GPT is linked to injury.