Despite the assessment of local/systemic complications, it was recently demonstrated that Serum Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) [29], serum uromodulin [30], and serum neutrophil gelatinase-associated lipocalin (NGAL) [31] could serve as reliable early predictors of AP severity. Here, LCN2 is linked to alkaline phosphatase measurement.