EMT-inducing transcription factors (EMT-TFs) such as Twist1, Snail1, Slug, and Zeb1 play an essential role in cancer metastasis, being directly or indirectly involved in cancer cell metastasis through different signaling cascades [9,10,11,12,13,14,15,16,17], so regulating EMT-TFs might be an interesting potential approach in cancer therapeutics. This evidence concerns the gene TWIST1 and cancer.