As the upregulation of 90K in several cancers including colon, prostate, lung, and breast suggests an association between 90K and tumorigenesis [7,9,11,12], and E-cadherin depletion is directly related to migratory and metastatic properties of the cancer cell, here we aimed to analyze the effects of 90K on E-cadherin levels in cancer cell types that are known to exhibit varying degrees of migratory capability. Here, CDH1 is linked to cancer.