NUDT15 and Decreased total leukocyte count: Yang et al. reported that the NUDT15 allele encoding p.Arg139Cys was found in 89.4% of early leukopenia cases but in only 6.8% of controls, suggesting that the presence of the NUDT15 allele had a sensitivity of 89.4% and specificity of 93.2% for early leukopenia in Koreans [17].