The FAM5C gene has been associated with myocardial infarction [43] and functional studies have shown that it increases the production of ROS, nuclear factor-kappaB (NF-κB) activity, and expression of the intercellular and vascular cell adhesion molecules, ICAM-1 and VCAM-1 [44]. Here, NFKB1 is linked to myocardial infarction.