These eicosanoids are deeply involved in the inflammatory processes of IBD; they have a potent chemotactic action and an ability to recruit neutrophils, increase vascular permeability, promote platelet aggregation, cause oedema, and induce the release of pro-inflammatory substances, such as cytokines (soluble proteins influencing the immune system), which lead to the production of chronic inflammatory mediators, such as interleukin (IL) 1β, 6, and 8, and tumor necrosis factor α (TNFα) [11,45]. This evidence concerns the gene TNF and inflammatory bowel disease.