In fact, glucocorticoids can induce FKBP5 expression in the adipose tissue, where higher FKBP5 expression has been associated with markers of insulin resistance, such as insulin, homeostatic model assessment of insulin resistance, subcutaneous adipocyte diameter [158], and lower levels of plasma HDL (high-density lipoprotein)-cholesterol [158]. Here, FKBP5 is linked to Insulin resistance.