The High-B patient was a 67-year-old HER2 1 + group woman, with a 15 × 15 mm lesion of the papillotubular subtype of invasive ductal carcinoma, no lymph node metastasis, and immunohistochemistry staining also showing 90% ER, 80% PgR, and 5% Ki-67. Here, ERBB2 is linked to metastasis.