Specifically, greater depressive symptoms and high sleep complaints were both associated with female sex, non-cohabitation, having lower wealth, smoking, engaging in less physical activity, consuming alcohol less frequently, having a higher BMI, reporting a diagnosis of hypertension, CHD, diabetes/high blood glucose, pulmonary disease, or arthritis and having higher circulating levels of fibrinogen and hs-CRP (all p < 0.05). The gene discussed is CRP; the disease is Arthritis.