Our findings showed that older men and women reporting elevated depressive symptoms and/or sleep complaints shared a range of sociodemographic, behavioural and clinical correlates that included female sex, non-cohabitation, lower wealth, smoking, exercising less than once a week, drinking alcohol infrequently, higher BMI, having hypertension, CHD, diabetes/high blood glucose, pulmonary disease, and arthritis, as well as higher levels of hs-CRP and fibrinogen. The gene discussed is CRP; the disease is diabetes mellitus.