Compared with those without T2D, participants with T2D had not only significantly higher percentages of age ≥ 60, obesity, high TG and low HDL-c, but also higher age, BMI, SBP, TG, FBG and PBG levels, and lower HDL-c levels, at baseline, as well as higher hs-cTnT levels at baseline and follow-up (Table 2). This evidence concerns the gene TNNT2 and obesity due to melanocortin 4 receptor deficiency.