VEGFA and chronic kidney disease: Although the therapeutic use of compounds with anti-VEGF activity may prevent proteinuria in endothelial murine models of diabetic nephropathy10,11, the significance of VEGF/VEGFRs/sVEGFR1 modulation within the glomerular milieu, its contribution to GEC damage and progression of chronic kidney disease (CKD) is still not clearly understood.