RPGRIP1 and ciliopathy: A large library of ENU-mutagenized fish were screened by TILLING25 for mutations in zebrafish ciliopathy genes, a C → T transversion at nucleotide 2206 in exon 18 of the rpgrip1 gene was identified, resulting in a premature stop codon (Q736X) and loss of a BbvI restriction site, which was subsequently used for genotyping rpgrip1 mutants (Fig. 1B,C).