Next, we investigated whether IL-13Rα2 could provide a growth advantage in the presence of wtEGFR, using a tetracycline (Tet)-inducible wtEGFR (denoted as U251-E6) or mutant EGFRvIII (denoted as U251-E18) in the glioblastoma cell line U251MG. Here, IL13RA2 is linked to glioblastoma.