Human glioma Gli36 cells were chosen to constitutively express IL-13Rα2 alone, EGFRvIII or both receptors as confirmed by immunoblotting analysis and denoted as Gli36.IL-13Rα2, Gli36.EGFRvIII and Gli36.IL-13Rα2/EGFRvIII, respectively (Fig. 1e). Here, IL13RA2 is linked to glioma.