H. hepaticus-infected WT mice, which do not develop colitis, showed some evidence of increased infiltration by Ly6Chi MHCII−, Ly6C+ MHCII+, and Ly6C− cells, while uninfected Il10−/− mice had slightly higher numbers of Ly6C+ MHCII+ cells than their naive WT counterparts; however, these differences were modest and did not attain statistical significance (Fig. 3E). Here, IL10 is linked to colitis.