Diffuse HAI-1 expression (i.e., score 3) showed no correlation with major clinicopathological parameters, such as tumor size, the presence of lymph node metastasis, and tumor cell differentiation, and only older age (≥ 70) was correlated with the diffuse HAI-1 immunoreactivity (Table 1). The gene discussed is SPINT1; the disease is metastatic malignant neoplasm in the lymph nodes.