Western blot analysis showed that upregulating miR-141-3p reduced the expression of mesenchymal marker vimentin and fibronectin, and enhanced the expression of epithelial marker E-cadherin in PCa cells; conversely, silencing miR-141-3p increased vimentin and fibronectin expression, and decreased E-cadherin expression (Fig. 3c). The gene discussed is VIM; the disease is posterior cortical atrophy.