KCNIP2 and type 1 diabetes mellitus: Broadened ventricular repolarization and reduced ‘repolarization reserve’ in alloxan-induced T1DM in dogs may also involve impaired K+ currents as a result of reduced Kv4.3 (voltage-gated K+ channel subfamily D) and MinK (voltage-gated K+ channel sub-family E subunit) expression, while Kv1.4 (voltage-gated K+ channel subfamily A), KChIP2 and KvLQT1 (voltage-gated K+ channel subfamily D) were increased [452].