A palmitate enriched diet significantly depresses cardiac caveolin-3 [276], whereas a flaxseed-enriched diet reverses reductions in cardiac caveolin-3 in cardiomyopathic hamsters [278], and prevents reductions in skeletal muscle caveolin-3 in a model of muscular dystrophy (also repairing sarcolemmal damage, reducing inflammation and cell death) [459]. The gene discussed is CAV3; the disease is muscular dystrophy.