Using hospital discharge data to analyze hospital admission and/or readmission rates, the rate of a particular surgical procedure, or adherence to recommended therapy by genotype could incorrectly classify up to 15% of individuals with SCA, three-fourths of those with Hb SC, and over two-thirds of those with Hb Sβ+ thalassemia. The gene discussed is GSTM1; the disease is thalassemia.