The purpose of this study was to use the hospital discharge records of a population-based sample to (1) describe the extent of miscoding for the major SCD genotypes and estimate the accuracy of ICD-9-CM codes and (2) report the positive predictive value of using Hb SS ICD-9-CM codes only (282.61 and 282.62) to identify individuals with SCA. The gene discussed is GSTM1; the disease is Schnyder corneal dystrophy.