NFKB1 and infection: To determine whether NF-κB enhances Ad gene expression and the replication of TRAD in hepatocytes, in the present study we pretreated PH5CH8 cells20 (a non-neoplastic human hepatocyte cell line) with an NF-κB inhibitor BAY11-7082 and a proteasome inhibitor MG-132, followed by infection with the conventional TRAD.