They also identified a parallel increase between the severity of the H. pylori gastritis and NLR values.20 In another study conducted by Jafarzadeh et al,21 it was established that the H. pylori-positive patients, independent of the bacterial cytotoxin-associated gene A (CagA) status and regardless of peptic ulcer, had more leukocyte, neutrophil, and NLR ratios in their blood than that of the H. pylori-negative patients. This evidence concerns the gene S100A8 and gastritis.