However, comparison between HBV-positive cirrhosis and HBV-negative cirrhosis showed that IP-10 (p = 0.003) and p53 (p = 0.0072) were significantly decreased in HBV-positive cirrhosis, but Foxp3 (p = 0.0004) was significantly increased in HBV-positive cirrhosis (Graph 1). The gene discussed is TP53; the disease is Cirrhosis.