GGTLC1 and metabolic dysfunction-associated steatohepatitis: Gamma-glutamyltranspeptidase, therefore, has an important role in antioxidant defense systems at the cellular level and is a valuable marker of oxidative stress in NAFLD.9, 10 We have reported that levels of GGT in FL patients may compensate for mild oxidative stress by repressing 8-OHdG levels and preventing progression to NASH; oxidative stress leads to increased levels of 8-OHdG and the development of NASH.11 It may also contribute to clinical progression from simple FL to NASH.