Studies have reported that up to 85% of individuals with Child–Pugh C cirrhosis have varices as compared to only 45% those with Child–Pugh A cirrhosis.8 On the contrary, plasma prothrombin time is one of the coagulation tests that detects the coagulation defect and certain diseases like chronic parenchymal liver diseases. The gene discussed is F2; the disease is Cirrhosis.