MMP7 and neoplasm: Matrix metalloproteinase-7 (MMP-7) is also known as matrilysin and plays a role in apoptosis, angiogenesis, tumor growth, invasion and metastasis.2 In addition, MMP-7 activates other metalloproteinases, such as MMP-2 and MMP-9 and these may affect ECM and causes the invasion of cancer cells.