MMP7 and polyp: In one study, MMP-7 was shown to be focally over-expressed in about 50% of benign adenomas,12 while another study reported that MMP-7 expression was higher in areas of tumor that were more dysplastic and invasive.13 Moreover, the overexpression of MMP-7 was observed in all cases with familial adenomatous polyposis regardless of the polyp size and the degree of dysplasia.14 However, there is lack of consensus about this.