Hepatitis B surface antigen was prevalent among the adults with acute hepatitis (46%).6 The prevalence of anti-HBc ranged from 38.5% among adults in Siem Reap province to 58.6% among blood donors.7 The prevalence of both positive for HBsAg and anti-HBc was 7.3%.7 Genotype C represented 86% (99% was C1) followed by genotype B (11.6%). The gene discussed is KRT88P; the disease is Acute hepatitis.