PLOD1 and polycystic ovary syndrome: The analysis of LH in PCOS and treated groups with curcumin (100 and 200 mg/kgBW) compared with the control group (p<0.001) was done, but at other doses of curcumin (300 and 400 mg/kgBW), decreased LH serum levels showed no significant change compared with the PCOS group.