KRAS and cancer: By this caveolar endocytic route, CNPs rendered efficient let‐7a delivery to cancer cells in target tissue, as evidenced by a reduction of KRAS expression by 50% in cancer cells postincubation with CNPs for 4 h and increase in let‐7a expression by 1.5‐fold and decline of KRAS expression by threefold in tumors treated with CNPs.