SRY and Myocardial fibrosis: When human SRY (hSRY) is inserted into single-cell mouse embryos (hSRYON), this early activation of SRY results in impaired brain neurogenesis and several other disorders, including inability of the resulting pups to suckle, development of fatty liver disease, arrested alveologenesis in the lung, sporadic myocardial fibrosis, and thymic hypoplasia (Kido et al., 2017).