Since this pregnancy-specific decrease was absent in AP group (AP 111.7 [98.84–125.6] versus ANP 109.2 [95.59–116.3] μg/mL), we could demonstrate a significant difference between the clusterin levels of the two pregnant groups (111.7 [98.84–125.6] μg/mL in AP versus 98.80 [84.26–105.5] μg/mL in HP, p = 0.0091; Figure 3 and Table 1). This evidence concerns the gene CLU and alkaline phosphatase measurement.